Colorectal cancer is among the largest cancer burdens in the world today. Nearly 1.4 million people are diagnosed and almost half this number will die from the disease this year1. Although Japan represents the worlds highest incidence of the disease, Europe represents the highest risk for death from colorectal cancer2. In Europe, CRC is the third most common cancer and is one of the leading causes of cancer death, with 500,000 new cases and a quarter million deaths expected in 2018. And with aging demographics in the industrialized regions, the unmet medical need is expanding: death from CRC is expected to nearly double within the next 20 years3.